The defending American League champion have struggled to get traction so far in the 2021 season, but they are hoping to end an extended stay at Tropicana Field on a high note. They host the similarly middling on Friday at 7:10 p.m. ET for the first of a three-game Indiana Pacers Hoodie set. The Rays are coming off a four-game split against the , while the Astros head to Tampa with some momentum after taking three of four at home against the . Left-hander is expected to take the mound for Tampa Bay, while veteran right-handed starter Jr. set to go for Houston. Houston is a -120 favorite (risk $120 to win $100), while Tampa Bay is offered at +110 in the latest William Hill Sportsbook odds for Astros vs. Rays. This American League matchup is just one on a ma sive 15-game slate for Friday. Others of note include and the (-140) visiting the , who will counter with veteran . Before making any MLB picks or predictions on those games or others, you need to .This model, which simulates every pitch of every game 10,000 times, had a banner 2019 season, the league's last full schedule, returning more than Jermaine O'Neal Jersey $1,400 on its top-rated money-line and run-line . It is off to a profitable start in 2021, going 29-21 on top-rated MLB money-line picks through four weeks, returning over $250. Anyone following it has seen huge rewards.Now, the model has T. J. Warren Jersey crunched the numbers for the Friday MLB schedule and posted its best bets for the evening games. Parlaying these four MLB picks would pay well over 13-1. .Top MLB picks for Friday, April 30The model likes the suddenly hot Oakland Athletics (-130) to defeat the , with first pitch set for 9:40 p.m. ET from the Oakland Coliseum. The Athletics got off to a dismal 0-6 start in which their pitching staff allowed eight or more runs five times. Their lineup didn't fare much better, scoring a total of 13 runs in that span with a game-high of five. However, they soon did an about-face and countered the losing with a 13-game winning streak marked by dominance from their pitching staff. Oakland held its opponents to two or fewer runs right times during that streak, which included four shutouts.The Athletics are coming off a tight four-game series against the Rays that was defined by strong pitching on both sides. hit the go-ahead double in the Jeremy Lamb Jersey ninth inning on Thursday for the difference in a 3-2 win that salvaged a 2-2 series split. Featured Game | Oakland Athletics vs. Baltimore Orioles Moneyline Spread Bojan Bogdanovic Jersey Total OAK BAL How to make MLB predictions, parlays for Friday, April 30The model has locked in three other MLB best bets, including a strong play on an underdog that helps push this parlay to a huge return. . So which MLB picks should you make on Friday for a shot at a big return of well over 13-1? And which underdog do you need to be all over? , and find out.