It isn't often that a one-game series takes place in Major League Baseball, but that is the case on Monday evening at American Family Field. The welcome the to town for a one-off tilt. The game was previously scheduled for early April as part of a Dwight Howard Jersey full series, though things were shuffled after the 2022 season was delayed. San Francisco enters at 11-5 this season, and Milwaukee boasts a 10-6 record.Caesars Sportsbook lists Milwaukee as the -190 money-line favorite (risk $190 to win $100) for this 6:10 p.m. ET first pitch. The total number of runs Vegas thinks will be scored, or the over-under, is seven in the latest Brewers vs. Giants odds. Before making any Giants vs. Brewers picks, The SportsLine Projection Model simulates every game 10,000 times and it is off to a sizzling start to the 2022 season. It's on a 25 Cassius Winston Jersey -11 roll on top-rated through three weeks, returning almost $1,100 for $100 players. Anyone following it has seen huge returns.Now, the model has locked in on , and just locked in its picks and MLB predictions. . Here are the and trends for Brewers vs. Giants: Giants vs. Brewers money line: Brewers -190, Giants +170Giants vs. Brewers over-under: 7 runsGiants vs. Brewers run line: Brewers -1.5 (+105)SF: The Giants are 7-3 in road gamesMIL: The Brewers are 5-2 in home games Featured Game | Milwaukee Brewers vs. San Francisco Giants Moneyline Spread Total MIL SF Why you should back the GiantsPlenty of attention will be paid to Milwaukee's starting pitching option, and rightly so, but the Giants also project well in run prevention. San Francisco ranks in the top three of Major League Baseball with a staff ERA of 2.51, and the bullpen is tremendous. The Giants are set to deploy the equivalent of a bullpen game on Monday, though 29-year-old will open things up. He has thrown 4.2 innings of scorele s baseball this season acro s four appearances and, when Long leaves the game, he will be flanked by a Giants relief corps that leads the NL with a Ian Mahinmi Jersey 1.71 ERA in 63 innings.San Francisco's relievers have a 49.7 percent ground ball rate and have allowed only 0.43 home runs per nine innings. Milwaukee is below-average offensively in the early going, landing below the NL median in batting average, slugging percentage, on-base percentage, home runs and runs scored. On offense, the Giants rank in the top Robin Lopez Jersey three of the NL with 79 runs scored and 17 home runs. San Francisco is clearly above-average at the plate, and the Giants are coming off a 2021 campaign in which they were near the top of the NL in virtually every offensive category.Why you should back the BrewersThe Brewers have a patient approach at the plate, producing a walk in nearly 10 percent of plate appearances. Milwaukee also has a strong defensive projection but, more than anything, the Brewers can lean on one of the best starting pitchers on the planet in this matchup. , the 2021 Cy Young award winner, takes the ball for Milwaukee, and he led the National League with a 2.43 ERA last season. Burnes also had the best strikeout rate of any National League pitcher, striking out 12.6 batters per innings. He also walked only 1.8 batters per nine innings in 2021, and Burnes led the league with 6.88 times as many strikeouts as walks. Beyond that, he is excellent at preventing home runs, leading the league with 0.377 home runs per nine Thomas Bryant Jersey innings, and the 2022 season is also going well for Burnes. Through three starts, he has navigated 19.0 innings with a 2.37 ERA and more than 10 strikeouts per nine innings. That includes 18 strikeouts and only two earned runs allowed in his last 14 innings acro s two starts.How to make Brewers vs. Giants picksSportsLine's model is leaning over on the run total, as the simulation suggests the teams will combine for 7.5 runs. It also says one side of the money line has all the value. .So who wins Giants vs. Brewers? And which side of the money line has all the value? , and find out.